I've managed to get this working, seems like it was a problem within the index.php file rather than .htaccess in the end.
In my scripts for all the image locations it is doing it as the new directory, /images
so its trying to say the images are in /word1/word2/word3/images
rather than /images
This is probably since the file locations are like this:
Is there any way to make sure it does treat it in the right directory, rather than me having to replace them all with http://www.domain.com/images/image.gif
Also, it no longer lets me browse directories which were there previously, which have contents in which I need to view, it just returns the index page