Damn.. I spent a lot of time playing with this before posting my question. Suddenly, after posting it, I have resolved it. (sigh)
var newVar = "A string of new text";
var targetID = $('.rowFocus');
var childs = targetID.children('classD');
If anyone knows of a website that can offer ColdFusion help that isn't controlled by neurotic, pedantic jerks* (stackoverflow.com), please PM me with a link.
* The neurotic, pedantic jerks are not the owners; just the people who are in control of the "popularity contest".